Motif ID: STAT5{A,B}.p2

Z-value: 0.802


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Achr17_+_376940070.175.4e-01Click!
STAT5Bchr17_-_37681917-0.058.6e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_39860398 2.077 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr20_-_42713663 1.890 ADA
adenosine deaminase
chr20_-_42713778 1.863 NM_000022
ADA
adenosine deaminase
chr19_+_62972808 1.278 NM_017652
ZNF586
zinc finger protein 586
chr19_+_62972861 1.270 ZNF586
zinc finger protein 586
chr14_+_23700261 1.259 NM_006084
IRF9
interferon regulatory factor 9
chr1_-_31003260 0.926 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr19_+_49361054 0.825 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr11_-_82674546 0.824 CCDC90B
coiled-coil domain containing 90B
chr1_+_148137778 0.783 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr6_-_32892705 0.770 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr19_-_49131250 0.750 NM_003425
ZNF45
zinc finger protein 45
chr1_-_219977424 0.712 NM_144728
DUSP10
dual specificity phosphatase 10
chr6_+_84626113 0.690 CYB5R4
cytochrome b5 reductase 4
chr19_+_49408523 0.648 NM_182490
ZNF227
zinc finger protein 227
chr6_+_116707975 0.627 NM_001080976
LOC100506515
DSE
hypothetical LOC100506515
dermatan sulfate epimerase
chr6_-_159160386 0.620 EZR
ezrin
chr6_+_84626083 0.608 NM_016230
CYB5R4
cytochrome b5 reductase 4
chr6_-_159160387 0.598 EZR
ezrin
chr6_+_84626146 0.596 CYB5R4
cytochrome b5 reductase 4
chr19_+_39916935 0.573 ZNF181
zinc finger protein 181
chr11_-_82675024 0.569 NM_021825
CCDC90B
coiled-coil domain containing 90B
chr6_-_159160355 0.568 EZR
ezrin
chr6_-_159160421 0.523 NM_001111077
EZR
ezrin
chr22_+_37407906 0.521 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr1_-_158883666 0.513 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr22_+_37407921 0.511 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chrX_-_154216929 0.510 NM_001289
CLIC2
chloride intracellular channel 2
chr22_+_37407925 0.503 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr22_+_37407899 0.477 NM_020243
TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr12_+_132167057 0.468 NM_003440
ZNF140
zinc finger protein 140
chr22_+_48966394 0.450 TRABD
TraB domain containing
chr6_-_27548438 0.419 NM_007149
ZNF184
zinc finger protein 184
chr1_-_201420927 0.408 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr12_+_132167551 0.392 ZNF140
zinc finger protein 140
chr20_-_18425811 0.391 NM_006606
RBBP9
retinoblastoma binding protein 9
chr20_+_34019942 0.376 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr10_+_124903874 0.375 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr1_-_33275071 0.368 NM_013411
AK2
adenylate kinase 2
chr2_-_230792844 0.366 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr5_+_178219519 0.356 NM_058230
ZNF354B
zinc finger protein 354B
chr7_-_132417374 0.356 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr15_+_73102984 0.355 PPCDC
phosphopantothenoylcysteine decarboxylase
chr12_+_132167512 0.352 ZNF140
zinc finger protein 140
chr15_+_39853982 0.345 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr12_+_11694172 0.341 ETV6
ets variant 6
chr19_+_49198916 0.341 NM_006300
ZNF230
zinc finger protein 230
chr15_+_39853923 0.336 NM_001128608
NM_014994
MAPKBP1

mitogen-activated protein kinase binding protein 1

chr1_-_31003181 0.321 LAPTM5
lysosomal protein transmembrane 5
chr19_+_49180171 0.317 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr19_+_17239264 0.301 BABAM1
BRISC and BRCA1 A complex member 1
chrX_+_107174855 0.299 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr15_-_57452345 0.265 MYO1E
myosin IE
chr15_+_73102979 0.264 NM_021823
PPCDC
phosphopantothenoylcysteine decarboxylase
chr12_-_44670632 0.263 NM_004719
SCAF11
SR-related CTD-associated factor 11
chr15_-_81527109 0.261 NM_001011885
NM_025238
BTBD1

BTB (POZ) domain containing 1

chr1_-_33275015 0.257 AK2
adenylate kinase 2
chr19_+_62836322 0.245 NM_006385
NM_198855
ZNF211

zinc finger protein 211

chrX_-_153903963 0.243 NM_000132
F8
coagulation factor VIII, procoagulant component
chr19_+_17239148 0.241 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1

chr9_+_111582317 0.239 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr1_-_54291474 0.236 TMEM59
transmembrane protein 59
chrX_+_48219344 0.235 NM_012280
NM_177439
FTSJ1

FtsJ homolog 1 (E. coli)

chr1_-_54291503 0.233 TMEM59
transmembrane protein 59
chr15_+_89444185 0.230 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr11_+_85690900 0.225 NM_016401
C11orf73
chromosome 11 open reading frame 73
chr7_+_80113570 0.224 NM_001127443
NM_001127444
CD36

CD36 molecule (thrombospondin receptor)

chr12_-_44670613 0.224 SCAF11
SR-related CTD-associated factor 11
chr1_-_54291378 0.223 TMEM59
transmembrane protein 59
chr17_-_5263594 0.218 NUP88
nucleoporin 88kDa
chr15_-_81526896 0.218 BTBD1
BTB (POZ) domain containing 1
chr12_+_12857516 0.214 NM_016355
NM_201224
DDX47

DEAD (Asp-Glu-Ala-Asp) box polypeptide 47

chr16_-_69030421 0.211 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr19_-_49696322 0.210 NM_013256
ZNF180
zinc finger protein 180
chr9_+_129226473 0.210 NM_007135
ZNF79
zinc finger protein 79
chr15_-_57452361 0.206 NM_004998
MYO1E
myosin IE
chr22_-_37232290 0.203 NM_001098504
NM_006386
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr19_-_55220495 0.202 NM_001025778
NM_016440
VRK3

vaccinia related kinase 3

chr7_-_149960612 0.199 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr3_+_197951203 0.197 PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr5_+_61637701 0.196 NM_001098511
NM_004520
KIF2A

kinesin heavy chain member 2A

chr3_+_181802592 0.192 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chrX_+_46935152 0.184 UBA1
ubiquitin-like modifier activating enzyme 1
chr4_+_86615275 0.184 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr22_-_37232246 0.183 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr5_+_85949511 0.180 COX7C
cytochrome c oxidase subunit VIIc
chr2_+_43854681 0.177 NM_001193464
NM_015522
NM_016008
DYNC2LI1


dynein, cytoplasmic 2, light intermediate chain 1


chr5_+_85949518 0.172 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr19_-_41711009 0.171 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr6_+_139136349 0.164 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr4_+_174528675 0.162 SAP30
Sin3A-associated protein, 30kDa
chr1_-_33275039 0.162 AK2
adenylate kinase 2
chr22_-_37232227 0.161 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr1_-_27834210 0.160 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr5_-_178090203 0.159 NM_005649
ZNF354A
zinc finger protein 354A
chr19_+_49221333 0.159 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr16_+_52025891 0.156 RBL2
retinoblastoma-like 2 (p130)
chr7_-_132417237 0.154 NM_017812
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_-_111120817 0.153 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr20_+_62164900 0.152 TCEA2
transcription elongation factor A (SII), 2
chr11_-_133628348 0.150 NM_001037304
NM_001037305
NM_014174
NM_199297
NM_199298
THYN1




thymocyte nuclear protein 1




chr15_+_89444433 0.149 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr16_+_52025845 0.144 NM_005611
RBL2
retinoblastoma-like 2 (p130)
chr11_+_133628616 0.142 NM_014384
ACAD8
acyl-CoA dehydrogenase family, member 8
chr4_+_174528602 0.142 NM_003864
SAP30
Sin3A-associated protein, 30kDa
chr1_-_33275057 0.139 NM_001625
AK2
adenylate kinase 2
chr16_+_52025863 0.139 RBL2
retinoblastoma-like 2 (p130)
chr15_+_64661560 0.137


chr1_+_203503214 0.135 TMCC2
transmembrane and coiled-coil domain family 2
chr12_+_21175394 0.132 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr14_-_81069951 0.129 NM_005065
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr16_+_52025874 0.129 RBL2
retinoblastoma-like 2 (p130)
chr19_-_63205948 0.127 ZNF606
zinc finger protein 606
chr19_-_50601406 0.124 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr18_-_41938196 0.121 NM_001001937
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr8_-_66708967 0.120 NM_018120
ARMC1
armadillo repeat containing 1
chr8_-_66708948 0.118 ARMC1
armadillo repeat containing 1
chr1_+_38250995 0.113 UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr9_+_15412862 0.111 SNAPC3
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr17_+_65009986 0.111 MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_63669596 0.108 NM_005917
MDH1
malate dehydrogenase 1, NAD (soluble)
chr14_+_67356248 0.107 NM_002877
NM_133509
NM_133510
RAD51L1


RAD51-like 1 (S. cerevisiae)


chr11_+_2877486 0.106 NM_183233
SLC22A18
solute carrier family 22, member 18
chr9_+_15412875 0.104 SNAPC3
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr17_+_30938433 0.104 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr19_-_55220439 0.100 VRK3
vaccinia related kinase 3
chr3_+_132228383 0.098 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr19_+_55221106 0.098 ZNF473
zinc finger protein 473
chr13_-_51276231 0.098 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr8_+_124154079 0.098 NM_001145088
NM_145647
WDR67

WD repeat domain 67

chr18_-_42815965 0.097 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr14_-_81069865 0.096 SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr14_+_96333434 0.096 NM_003384
VRK1
vaccinia related kinase 1
chr17_+_30938470 0.096 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr8_-_102034730 0.095 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_+_124154117 0.094 WDR67
WD repeat domain 67
chr19_+_39917319 0.092 NM_001029997
NM_001145665
ZNF181

zinc finger protein 181

chrX_-_48818585 0.091 NM_007213
PRAF2
PRA1 domain family, member 2
chr5_+_140733664 0.091 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr1_-_202726068 0.090 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr1_-_54291634 0.089 NM_004872
TMEM59
transmembrane protein 59
chr6_-_41276901 0.088 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chr19_-_63119746 0.087 NM_152475
ZNF417
zinc finger protein 417
chr1_+_153374900 0.087 NM_001122837
NM_001122839
NM_018845
SLC50A1


solute carrier family 50 (sugar transporter), member 1


chrX_+_46935035 0.086 NM_153280
UBA1
ubiquitin-like modifier activating enzyme 1
chr10_-_121345968 0.085 TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr13_+_24844084 0.085 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr1_+_177317856 0.083 TOR3A
torsin family 3, member A
chr14_-_19951417 0.083 NM_007110
TEP1
telomerase-associated protein 1
chr19_+_49268106 0.083 NM_001037813
ZNF284
zinc finger protein 284
chr7_-_107883929 0.083 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr1_+_53165545 0.082 SCP2
sterol carrier protein 2
chr16_-_66528235 0.082 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_153374967 0.082 SLC50A1
solute carrier family 50 (sugar transporter), member 1
chr19_-_63018092 0.078 NM_024762
ZNF552
zinc finger protein 552
chr5_+_32621361 0.078 NM_006713
SUB1
SUB1 homolog (S. cerevisiae)
chr17_+_15543771 0.077 ZNF286A
zinc finger protein 286A
chr12_-_47735373 0.076 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr19_+_40900965 0.075 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr3_+_199161446 0.075 NM_000996
RPL35A
ribosomal protein L35a
chr22_+_48966480 0.075 NM_025204
TRABD
TraB domain containing
chr8_+_18111894 0.074 NM_000662
NM_001160170
NM_001160171
NM_001160172
NM_001160173
NM_001160175
NM_001160176
NAT1






N-acetyltransferase 1 (arylamine N-acetyltransferase)






chr2_+_74594093 0.073 TLX2
T-cell leukemia homeobox 2
chr17_+_36665161 0.073 NM_030975
KRTAP9-9
keratin associated protein 9-9
chr8_-_109330116 0.073 NM_001568
EIF3E
eukaryotic translation initiation factor 3, subunit E
chr8_-_109330101 0.072 EIF3E
eukaryotic translation initiation factor 3, subunit E
chr12_-_10215942 0.072 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr14_-_76993641 0.071 NM_001193314
NM_001193315
NM_001193316
NM_001193317
NM_022067
VIPAR




VPS33B interacting protein, apical-basolateral polarity regulator




chr16_+_52025907 0.071 RBL2
retinoblastoma-like 2 (p130)
chrX_+_46318135 0.070 NM_019886
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr8_-_99375739 0.069 NM_024759
NIPAL2
NIPA-like domain containing 2
chr2_-_170138558 0.069 NM_024622
FASTKD1
FAST kinase domains 1
chr5_+_68702617 0.069 NM_133340
NM_133341
RAD17

RAD17 homolog (S. pombe)

chr3_-_120861959 0.069 NM_022135
POPDC2
popeye domain containing 2
chr2_+_171999042 0.067 DCAF17
DDB1 and CUL4 associated factor 17
chr9_+_129226535 0.066 ZNF79
zinc finger protein 79
chr1_+_53165488 0.065 NM_001007098
NM_001193599
NM_001193600
NM_001193617
NM_002979
SCP2




sterol carrier protein 2




chr19_-_52710129 0.065 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr22_-_37232261 0.065 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr19_+_40900757 0.064 NM_014727
MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr7_+_142670711 0.063 GSTK1
glutathione S-transferase kappa 1
chr8_-_101384633 0.063 NM_015435
RNF19A
ring finger protein 19A
chr10_-_103805858 0.063 NM_024541
C10orf76
chromosome 10 open reading frame 76
chr17_+_7457988 0.062 SHBG
sex hormone-binding globulin
chr6_-_166502119 0.062 NM_003181
T
T, brachyury homolog (mouse)
chr2_+_88772281 0.062 NM_144563
RPIA
ribose 5-phosphate isomerase A
chr15_+_46411646 0.062 NM_001948
DUT
deoxyuridine triphosphatase
chr20_-_25625173 0.062 NM_015655
ZNF337
zinc finger protein 337
chr1_+_242283129 0.061 NM_006352
ZNF238
zinc finger protein 238
chr7_+_98940537 0.060 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr12_+_54611212 0.060 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr11_+_67130898 0.058 NM_001166102
NM_007103
NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

chr7_+_98940208 0.057 NM_145102
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr19_+_63679563 0.057 NM_017908
ZNF446
zinc finger protein 446
chr1_-_33275051 0.056 AK2
adenylate kinase 2
chr7_+_142539291 0.054 NM_002652
PIP
prolactin-induced protein
chr7_-_150385867 0.054 CDK5
cyclin-dependent kinase 5
chr15_+_40427592 0.053 NM_212465
CAPN3
calpain 3, (p94)
chr7_+_142695511 0.053 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr9_-_133945064 0.052 NM_004269
CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.